38,579 Jobs Available In Columbus, OH

Scientist I, Early Stage Process Development

Posted on:
06/21/2021

Sarepta Therapeutics

Columbus, OH, USA

The Scientist I, Early Stage Process Development, actively participates in building of a new upstream processing lab and plays a critical role in the . . .

Posted on:
06/21/2021
Apply Before:
07/19/2021

Catering Sales Coordinator

Posted on:
06/21/2021

Levy Restaurants.

Columbus, OH, United States

Be part of the Excitement with Levy at the Columbus Convention Center! We are looking for people like you to join our team as we bring the best Ohio . . .

Posted on:
06/21/2021
Apply Before:
07/19/2021

Deputy ISC Director

Posted on:
06/21/2021

Study Group

Columbus, OH, USA

Contract Type: Permanent, full time JOB OVERVIEW We are excited to announce that we are recruiting for a Deputy Director to join in a senior leadersh. . .

Posted on:
06/21/2021
Apply Before:
07/19/2021

I.T. Professional Recruiting

Posted on:
06/21/2021

Enterprise Search Associates

Columbus, OH, United States

Back To List TITLE: Perfusionist LOCATION: Columbus, Ohio Are you considering a career change? Looking for a smaller community(25K population), tha. . .

Posted on:
06/21/2021
Apply Before:
07/19/2021

Director Enterprise Sales - Ohio

Posted on:
06/21/2021

AXA Venture Partners SAS

Columbus, OH, United States

Job Requirements We are looking for a Director of Enterprise Sales to join our growing team! As the Director of Enterprise Sales, you are an indivi. . .

Posted on:
06/21/2021
Apply Before:
07/19/2021

Sr Operations Manager - Fleet Maintenance - Columbus, OH

Posted on:
06/21/2021

Ryder

Columbus, OH, USA

Current Employees: If you are a current employee at Ryder (not a Contractor or temporary employee through a staffing agency), please click here to log. . .

Posted on:
06/21/2021
Apply Before:
07/19/2021

Nuclear Medical Technologist

Posted on:
06/21/2021

Spaulding Associates

Columbus, OH, United States

Navigation Spaulding Associates Recruiting Services in Power Engineering and Big Data (207) 967-2883 info@spaulding-associates.com Home main-nav Home . . .

Posted on:
06/21/2021
Apply Before:
07/19/2021

OSU Event Parking

Posted on:
06/21/2021

Valet Parking Service

Columbus, OH, United States

Want to hear something crazy? Cars only spend 5% of their time driving.  Where do they spend the other 95%?   PARKED! LAZ Parking is one of the lar. . .

Posted on:
06/21/2021
Apply Before:
07/19/2021

Improveit 360 - Customer Relationship Manager (Remote)

Posted on:
06/21/2021

Listen360, Inc.

Remote, USA

You: Relationship Managers are the face of improveit 360 – the primary advocate and front-line navigator for customers in their long-term partnershi. . .

Posted on:
06/21/2021
Apply Before:
07/19/2021

Improveit 360 - Sales Development Representative

Posted on:
06/21/2021

Listen360, Inc.

Columbus, OH, USA

improveit 360 is seeking a talented sales development representative, who will act in a lead development role to help prospects through the sales funn. . .

Posted on:
06/21/2021
Apply Before:
07/19/2021

Power Engineering And Big Data

Posted on:
06/21/2021

Spaulding Associates

Columbus, OH, United States

Title: Care Management Consultant-Population Health(Healthcare setting) Location: Columbus, OH Are you considering a career change? Looking for a sma. . .

Posted on:
06/21/2021
Apply Before:
07/19/2021

Maintenance Technician

Posted on:
06/21/2021

Spaulding Associates

Columbus, OH, United States

2+ years' experience repairing industrial processing equipment in an industrial environment or in the military Ability to read maintenance literature . . .

Posted on:
06/21/2021
Apply Before:
07/19/2021

Team Member Morse Rd

Posted on:
06/21/2021

Sbarro

Columbus, OH, United States

Job Description Team Member Summary Reporting to the General Manager, the Team Member provides front-line service to Sbarro guests in an enthusiasti. . .

Posted on:
06/21/2021
Apply Before:
07/19/2021

Equipment Rental Specialist

Posted on:
06/21/2021

Sunbelt's Employee Referral

Columbus, OH, United States

Job Description Join Our Team! Sunbelt Rentals strives to be the customer's first choice in the equipment rental industry. From pumps to scaffolding . . .

Posted on:
06/21/2021
Apply Before:
07/19/2021

I.T. Professional Recruiting

Posted on:
06/21/2021

Enterprise Search Associates

Columbus, OH, United States

Back To List TITLE: Ultrasonographer(Vascular Cardiology) LOCATION: Columbus, Ohio Are you considering a career change? Looking for a smaller commu. . .

Posted on:
06/21/2021
Apply Before:
07/19/2021

Scientist I, Early Stage Process Development

Sarepta Therapeutics

Columbus, OH, USA Apply Now
Share this job:

Job Type: Full Time

Key Skills:

training Internship - <p>if You Make Hearts Beat Faster, Your Own Has To Be In The Right Place. Key Skills

  • Aseptic Processing
  • Cryopreservation
  • Process Monitoring

Apply Now   
The Scientist I, Early Stage Process Development, actively participates in building of a new upstream processing lab and plays a critical role in the development of high quality and high yielding upstream processes for the production of AAV vectors using state of the art cell culture technologies and approaches. The candidate will be a key player in the design of robust cell culture processes from deep understanding of the variables impacting production of AAV vectors. The Scientist I closely collaborate with members of the Vector Core, Downstream Process Development, Analytical Development and additional internal/external groups in the design, development, and optimization of robust, fit-for-purpose, scalable cGMP ready manufacturing processes.

Primary Responsibilities Include:

  • Develop robust, well-characterized, high quality and high yielding upstream production processes for gene therapy viral vectors using mammalian adherent or suspension cell lines under the direction of senior team members
  • Plan and execute mammalian cell culture experiments at bench scale (shake flask, rocking bioreactors, AMBR15, and 1-50L SUB’s)
  • Design and execute process development studies to develop a thorough understanding of operating and performance parameters
  • Identify and implement operational improvements and novel technologies to improve upstream yield and key quality attributes of viral vectors
  • Prepare and review protocols, technical reports and SOPs for regulatory and tech transfer purposes
  • Participate and influence a cross-functional development team to advance production activities
  • Perform process analysis and trend process performance
  • Participate in technology transfer to manufacturing partners and provide oversight in process scale-up
  • Contribute to a safe, efficient and effective team environment with personal accountability
  • As a member of GTCOE work seamlessly with cross functional stakeholders within Tech Ops particularly Vector Core, Downstream and Analytical development team to facilitate translational research and to advance early stage gene therapy programs

Education and Skills Requirements: 

  • Advanced degree in scientific disciple required. Ph.D. in Bioengineering, Pharmaceutical Science, Biology, Biochemistry or related degree strongly preferred. 1-3 years of related experience.
  • Demonstrated expertise in mammalian cell culture techniques for adherent or suspension culture systems in batch and fed-batch modes. Previous experience in stable cell line development is a plus
  • Previous experience in media development for improving cell culture performance is desired
  • Experience in upstream techniques for production of biologics preferably with the use of bioreactors (rocking, stirred-tank) is highly desirable. Viral vectors production experience a plus
  • Experience in basic biochemistry laboratory techniques such as qRT-PCR, SDS-PAGE, Western blot, ELISA, etc. is expected
  • Experience in process design utilizing QbD and DoE principles via high-throughput approaches for process optimization is desirable.
  • Proficient in Microsoft office applications (Word, Excel, Powerpoint, Outlook) and knowledge of statistical software applications such as JMP, GraphPad Prism, etc. is a plus
  • Ability to think critically, and demonstrate troubleshooting and problem-solving skills
  • Self-motivated with a strong sense of ownership in areas of responsibility and willingness to accept temporary responsibilities outside of initial job description
  • Proven ability to successfully manage projects and timelines, organize/track complex information, prioritize accordingly, and the ability to quickly adjust to shifting priorities and demanding timelines when necessary.
  • Excellent communication skills with the proven ability to build open and collaborative relationships and work effectively as a member of a multidisciplinary team

Candidates must be authorized to work in the U.S.

Sarepta Therapeutics offers a competitive compensation and benefit package.

Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify.